Endocrine Abstracts

Aims: To evaluate thyroid gland dysfunction during interferon alfa (INF-alpha)therapy in patients with the hepatitis B virus (HBV) and hepatitis C virus (HCV)Methods: 58 patients with HCV and 18 patients with HBV were studied prospectively before and with 2 months intervals during INF-alpha therapy. Measurements of serum thyroxine,triiodothyronine, thyrotropine, triiodothyronine resin uptake, thyroid peroxidase antibodies (TPOAbs), and thyroglobulin anti...

Objectives: Hirsutism is a common clinical condition in women during reproductive age and characterized by excessive growth of terminal hair in the androgen-sensitive skin regions. Polycystic ovary syndrome (PCOS) and idiopathic hirsutism (IH) account for most of the cases of hirsutism. Insulin resistance and hyperinsulinemia have been demonstrated in women with PCOS and IH. We intended to investigate the degree of insulin resistance in women with PCOS compared to weight-match...

Objective: Genetic susceptibility to autoantibody formation in association with autoimmune thyroid disease and type 1 diabetes mellitus has been described with varying frequencies. We have, therefore, investigated the prevalence of anti-thyroid peroxidase (anti-TPO), overt and subclinical hypothyroidism in type 1 diabetic patients.Methods: Sixty-five subjects with type 1 diabetes mellitus and 65 unrelated normal controls were recruited for the detection ...